ODCs

Click node...

1 OMIM reference -
1 associated gene
10 signs/symptoms

PROTEIN INTERACTIONS: 1
COMMON SIGNS: 3

2 OMIM references -
1 associated gene
14 signs/symptoms

Testicular regression syndrome

Complete androgen insensitivity syndrome


INTERACTOME ASSOCIATIONS (click on a score value to see the evidence)	SRY	(0.87)	AR

Citations in the biomedical literature:

Testicular regression syndrome		Complete androgen insensitivity syndrome
	Synonym(s): - ETRS - Embryonic testicular regression syndrome - TRS - Vanishing testes syndrome - Vanishing testis syndrome		Synonym(s): - CAIS - Complete androgen resistance syndrome

	Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare endocrine disease - Rare genetic disease - Rare infertility - Rare urogenital disease		Classification (Orphanet): - Rare developmental defect during embryogenesis - Rare endocrine disease - Rare genetic disease - Rare gynecologic or obstetric disease - Rare infertility - Rare urogenital disease

	Classification (ICD10): - Congenital malformations, deformations and chromosomal abnormalities -		Classification (ICD10): - Endocrine, nutritional and metabolic diseases -

	Epidemiological data: Class of prevalence: 1-9 / 100 000 Average age onset: childhood Average age of death: - Type of inheritance: autosomal recessive		Epidemiological data: Class of prevalence: unknown Average age onset: variable Average age of death: normal Type of inheritance: x-linked recessive

	External references: 1 OMIM reference - No MeSH references		External references: 2 OMIM references - No MeSH references


COMMON SIGNS	- Male pseudohermaphrodism / lack of virilisation - Sterility / hypofertility - Uterine / uterus / Fallopian tubes anomalies

Testicular regression syndrome		Complete androgen insensitivity syndrome
	Very frequent - Ambiguous genitalia - Autosomal recessive inheritance - Late puberty / hypogonadism / hypogenitalism - Male internal genitalia anomaly / deferent ducts agenesis / ectopy / duplication - Micropenis / small penis / agenesis - Small / atrophic / hypoplastic testes / monorchism / microorchidism / anorchia Occasional - Face / facial anomalies		Very frequent - Decreased body hair / axillar / pubic hairlessness - Primary amenorrhea - Tall stature / gigantism / growth acceleration - Undescended / ectopic testes / cryptorchidia / unfixed testes Frequent - Inguinal / inguinoscrotal / crural hernia - Osteoporosis / osteopenia / demineralisation / osteomalacia / rickets Occasional - Contractures / cramps / trismus / tetania / claudication / opisthotonos - Gynecomastia / breast / mammary gland enlargement / hyperplasia - Sensitive trouble / deficit - Testicular / seminal neoplasm / tumor / carcinoma / cancer (excl. teratoma / germinoma) - Tremor